Kirsch's keynote speech, titled »From Process to Operation: Digital Twins for Filtration« uses examples to show how digital twins for individual process steps can be linked to form a digital process chain and how the entire product development process benefits from this holistic approach. Even the best filter material can only realize its full potential if its favorable properties are retained during processing and the operating conditions are right. Predicting the effects of the individual process steps on the end product using mathematical methods while keeping the computational effort within reasonable limits is an exciting challenge.